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October 3rd, 2008

End the spectre of science for sale

Posted by Dana Blankenhorn @ 1:06 pm

Categories: Drugs, Ethics, General, Mental Health, Rehabilitation, Research, U.S.

Tags: Dr., Emory University, ADHD, Mortgages, Regulations, Branding, Finance, Capital Structures, Government, Marketing

Dr. Charles Nemeroff, from his home page at Emory UniversityWhen I last wrote about the perception of scientists being paid for their conclusions, it was with the tongue-in-cheek observation that perhaps Massachusetts, by seeking to end the practice, might drive research out-of-state.

But the situation is far more serious, and hits closer to home, with the story of a researcher one critic dubbed “Bling-Bling.”

The nickname came from Dr. David Carlat, an ADHD researcher, in a 2006 post about Dr. Charles Nemeroff (above) of Emory University.

Emory is in Atlanta, where I live. Dr. Nemeroff chairs its psychiatry department. Dr. Carlat later apologized for calling Dr. Nemeroff “Bling-Bling,” but others soon took up the chant.

Now Dr. Nemeroff is being investigated for violating federal research rules, failing to report $1.2 million of income out of $2.8 million in consulting contracts he had with drug makers between 2001-2007.

An important point made by Dr. Carlat is that this was not an isolated case, that apparently it was fairly well-known, that this might just be called “doing business” in psychiatry.

It reminds me of the “crimes” being charged with respect to the “big shitpile” that Congress voted to bail-out today, in that there were no crimes committed. If the law and regulations let you create Confederate money, then outrage about the practice has nowhere to run.

The same is true here. If the law and regulations are not being violated, if only ethics are involved, then science for sale becomes standard practice.

Now let me tell you how this hits home.

John Blankenhorn in 2002Back in 2002 my ADHD son (son of an ADHD father) had a personal crisis. The details are unimportant, but I took the opportunity to have him looked at by competent professionals.

The doctor called me right away and said, “your son has ADHD.” Tell me something I don’t know, I responded.

The doctor put my son on Risperdal, the brand name for an antipsychotic drug called risperidone.

At the time Dr. Nemeroff was running a series of studies called ARISE, testing whether risperidone might be useful as an anti-depressant, or useful in the treatment of ADHD.

I have no evidence my son was part of that study. But if one respected person is testing a drug for a purpose, and this is known by others, chances are they might try it, too.

The answer my son gave was an emphatic no. He got no relief at all. He just got very tired. He felt awful. Once he left this professional’s care he immediately went off the drug, and his recovery began.

(That recovery continues. He will graduate from high school next spring, an honor student, and cost me a fortune at some elite college.)

Nemeroff’s risperidone study was published in a journal of which he was the editor, and he did not report his own financial conflict of interest, although the policy was he should have.

In any drug study like this, people are used as guinea pigs. They are beta testers, but their bodies are the computers on which the software runs.

That’s what is really at stake, when life sciences become corrupted. Think of what happened to my son as one sub-prime mortgage in a “big shitpile” of corruption.

Here’s the more important point. It was all legal. Dr. Nemeroff is not accused of any crime, and I doubt he will ever be accused. Maybe his reputation will be hurt. Maybe it won’t be.

But that does not make what happened to my son right. And if the profession has a care for its reputation, the next doctor who does something like this will have committed a crime.

Dana BlankenhornDana Blankenhorn has been a business journalist since 1978, and has covered technology since 1982. He launched the Interactive Age Daily, the first daily coverage of the Internet to launch with a magazine, in September 1994. See his full profile and disclosure of his industry affiliations.

Email Dana Blankenhorn

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  • Talkback
  • Most Recent of 13 Talkback(s)
John is now a senior
He knows what he wants to study -- history and political science. And he knows what he wants to do with it, the law.

I am trying to point him toward international law, where his experience lea... (Read the rest)
Posted by: DanaBlankenhorn Posted on: 10/06/08 You are currently: a Guest | | Terms of Use
Or Not  Yagotta B. Kidding | 10/03/08
There are also scholarships  DanaBlankenhornZDNet Moderator | 10/04/08
Requirements analysis  Yagotta B. Kidding | 10/04/08
John is now a senior  DanaBlankenhornZDNet Moderator | 10/06/08
They have us in a tough spot.  kozmcrae | 10/03/08
Must be October...  DanaBlankenhornZDNet Moderator | 10/04/08
I only found out recently myself.  kozmcrae | 10/04/08
re: - "It was all legal"  Takalok | 10/04/08
I can't accuse a doctor of breaking a law...  DanaBlankenhornZDNet Moderator | 10/04/08
Risperdal  frgough | 10/04/08
Please read the story again  DanaBlankenhornZDNet Moderator | 10/04/08
Your son's part in a study (and other matters)?  cd2_z | 10/05/08
I don't know that he was part of a study  DanaBlankenhornZDNet Moderator | 10/06/08

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